Professor Geoffrey Pilkington

Professor Geoffrey J Pilkington BSc PhD CBiol FSB FRCPath

HEAD OF GROUP

Present Appointment

  • Professor of Cellular and Molecular Neuro-oncology, School of Pharmacy and Biomedical Sciences
  • Head of Cellular and Molecular Medicine Research Division, Institute of Biomedical and Biomolecular Sciences

Previous Appointments

  • Professor of Experimental Neuro-oncology, King’s College London

Qualifications

  • BSc
  • PhD
  • CBiol
  • FSB
  • FRCPath

Society Memberships

  • President of the British Neuro-oncology Society
  • Fellow, Royal College of Pathologists (FRCPath)
  • Fellow, Society of Biology (CBiol FBS)
  • Fellow, Royal Society of Medicine
  • Member, European Association of Neuro-oncology
  • Member, Society for Neuro-oncology (USA)
  • Member, International Glioma Invasion Forum
  • Member, British Neuropathological Society
  • Member, International Society of Neuropathology
  • Member, European Association for Cancer Research
  • Member, British Neuroscience Association

Research Interests

  • Focuses on the development of models for the study of intrinsic brain tumours, elucidation of the mechanisms underlying diffuse local invasive behaviour in glioma and development of novel strategies for mitochondrial mediation of apoptosis in glioma.

Scientific Advisor

  • Brain Tumour UK
  • Brainstrust
  • Ali’s Dream & Charlie’s Challenge

Doctorate Supervision and Examination

  • Supervisor of 26 PhD candidates (at University of London, King’s College, London and University of Portsmouth)
  • Examiner of 31 PhD/MD candidates (at University of Cambridge, University of Nottingham, University of London, University of Sheffield, Queen’s University of Belfast, University of Glasgow, University of Edinburgh, the Open University, King’s College London, Imperial College London, Queen Mary London, University College London, the Peninsula Medical School,  University of Portsmouth, University of Lublijana, Slovenia, University of Bergen Norway, University of Gent Belgium, Dublin City University).

Journal Refereeing and Review of Grant Applications

  • Reviewer of articles for 53 different Scientific/Medical Journals. Editorial Board member of Anticancer Research, Oncology and Radiology and the Brazilian Journal of Medical and Biological Research
  • Reviewer for 25 UK grant giving bodies and 8 overseas bodies (The United States/Israel Binational Science Foundation, The Italian Association for Cancer Research (AIRC), the Cancer Society of New Zealand, The Royal Society of New Zealand, The Fonds National de la Recherche (CORE) Luxembourg, the Medical Research Council of South Africa, the New Zealand Neurological Foundation and the Israel Science Foundation). Also a member of the European Science Foundation (ESF) Reviewer’s Panel (2009-2012)

Geoff has spent his entire career in brain tumour research, having started work on chemical neuro-carcinogenesis where he studied brain cancer stem cells and brain tumour development at the Middlesex Hospital Medical School in the early 1970s and subsequently spent 23 years at the Institute of Psychiatry, King’s College, London, latterly as Professor of Experimental Neuro-oncology. In 2003 he moved to the School of Pharmacy & Biomedical Sciences, University of Portsmouth, as Professor of Cellular & Molecular Neuro-oncology & Director of Research. Over the years the research focus of his group has been development of models for the study of intrinsic brain tumours, elucidation of the mechanisms underlying diffuse local invasive behaviour in glioma and development of novel strategies for mitochondrial mediation of apoptosis in glioma.

Over the years Geoff has published numerous papers on the results of his research on human glioma and has developed various “all human” three-dimensional in vitro models to study brain tumour invasion and the blood-brain barrier. At the University of Portsmouth he has established an excellent suite of laboratories with two tissue culture laboratories and a host of state-of-the-art equipment including those to enable various assays including flow cytometry, cellular oxygen utilisation measurement, cell viability, apoptosis & proliferation assay and RT-PCR, to name a few. He has also established a sophisticated microscope imaging suite which includes atomic force microscopy, laser capture micro-dissection and live cell microscopy etc.

He was instrumental in the formation of Brain Tumour UK and remains as advisor to the charity. He is also advisor to Brainstrust Ali’s Dream & Charlie’s Challenge as well as formerly holding membership of the Samantha Dickson Brain Tumour Trust Scientific & Medical Advisory Board. He also works closely with Hammer Out and the Brain Tumour Research Campaign and is highly supportive of the new Brain Tumour Research consortium of brain tumour charities. He is also a regular attendee at the quarterly All Party Parliamentary Group meetings on Brain tumours at Westminster. He lives on the Isle of Wight and commutes daily across the Solent to his Portsmouth laboratories. In his spare time he lists his major interests as: rugby union, cricket, real ales and the Greek Islands.

Contact Details

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  • Getting Rid Of Stretch Marks
  • How Do I Get Rid Of Stretch Marks
  • Stretch Marks Before And After
  • Best Cream For Stretch Marks
  • How Can I Get Rid Of Stretch Marks
  • Stretch Marks On Legs
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    A stretch mark absolutely acquired stripe from your skin, narrow or broad, and frequently branched. Cloture typically How To Remove Stretch Marks Fast reddish Stretch Marks After Pregnancy generally and tend to end up with pale, which it is less elastic and looser than normal skin. The skin with the stripe may just be sunken or elevated, nonetheless an irregular bio oil reviews for stretch marks fashion. Bio Oil Stretch Marks Several stretch marks generally appear Bio Oil For Stretch Marks parallel.

    They can be cultivated anywhere in system, however, most often at places that have got a thick fat layer. remove stretch marks How To Get Rid Of Stretch Marks Typical places contain lower belly, the hips and your thighs. Stretchmarks are structural defects through the dermis, the mid layer of skin relating to the outer epidermis and in addition the inner fat-rich Stretch Marks After Pregnancy layer, subdermis. Affected regions have less fibers created the proteins elastin and collagen to preserve the skin layer taut and elastic. Skin scarring can form at any age throughout men or women, but highest risk occur during puberty as well as in mothers-to-be.

    One factor causing stretch marks is seen as a reduced manufacture of protein fibers with the skin as a result it gets weaker. This is certainly consequence of How To Remove Stretch Marks influence associated with an increased a higher level of glucocorticoid hormones which typically occur during puberty and pregnancy. Genetic inheritance or bad diet will be able to cause weaker skin. To the problems on occur your skin layer must then be stretched during severe amounts, either constantly or repeatedly, merely because of putting on weight, sport Get Rid Of Stretch Marks activities, pregnancy or external impacts.

    PREVENTION

    Keeping a standard weight can prevent striae, since a thick layer of fat ?Best Stretch Mark Removal Cream tissue generally seems to promote them. Primarily based research a great safety measure is massage of exposed body areas to have oily cream yet another definition gives moisture on to the skin. Examples of the ingredients employed in these preventive items are wheat germ oil, other Get Rid Of Stretch Marks Fast botanical oils, egg oil, panthenol, menthol, gotu kola extract and vit e. A little caution how body areas are stretched during sport and work may also help. The mentioned preventive steps can Stretch Mark Removal also heaps damage by having an initial How To Remove Stretch Marks Fast phase.

    TREATMENT

    Stretch marks normalize by time, but seldom go completely away. Laser facial treatment have shown to be capable so as to make striae less visible, How To Remove Stretch Marks particularly the fresh ones. By currently available laser skin treatment one uses light applying wavelength 585 nm inside the whole location to stimulate healing Bio Oil For Stretch Marks activities. Treatment with radio waves can also be Get Rid Of Stretch Marks effective, particularly alongside laser treatments.

    By permanently Stretch Mark Cream one performs many treatments where different spots in your striae are undergo the laser rays each time, and a second uses so strong light that small wounds are caused in those spots, fractional facial laser hair removal. Yet another How To Remove Stretch Marks regrowth activities will strengthen the dwelling also regarding the wounds which means your skin of your marks normalize. This remedy is considered to be just the thing for older striae.

    Sometimes one performs surgical abrasion while using the outer organ of the skin to accept away scars, Stretch Mark Removal called dermabaration. Microdermabration, where almost no a How To Remove Stretch Marks lot Get Rid Of Stretch Marks more than the outer layer of horn stuff, keratin, is can you get rid of stretch marks ground away, can even be options. These procedures Get Rid Of Stretch Marks Fast smoothen the top of skin, and his awesome regrowth activities will spread to deeper Best Stretch Mark Removal Cream facets of your epidermis and then make it tighter. When the truck driving overabundance of skin from an area, the excessive skin combined with scars can be taken out surgically, and your skin sewn together is tauter. Using this method is most often done towards the lower abdomen, and is also then called tummy tuck Stretch Mark Cream surgery.

    Creams with retinoids, which could be derivatives of vitamin a palmitate could help, especially retinoic acid. These substances may go by stimulating a good Stretch Marks After Pregnancy solid structural development at a dermis and epidermis. In a range of places these drugs are prescription bound.

    Products with the substance in your low concentration can be a program to treat scars. The substance dissolves irregular structures, mainly in the outer skin layer and eliminates miscoloration. The regrowth activities may then How To Remove Stretch Marks Fast establish a smoother and firmer structure. Merchandise, formulated as cleansers, scrubs or lotions shall usually remain on your skin a jiffy prior to being washed away. Several people Stretch Marks Removal report successes by simply Get Rid Of Stretch Marks using a retinoid cream and the substance in between each dose of your respective cream.

    Several manufacturers make creams, lotions or ointments with regard to stretch marks which really can be purchased without prescription. These will typically contain botanic oils of various kind to really make the skin smooth, one thing since a carrier of other working ingredients so that you can conditions cream an excellent consistency. Only 30 days . oils can be assumed to Stretch Marks After Pregnancy stimulate skin repair.

    Most advisors also contain vitamins, like vit a, vit e and Niacinamide (Niacin). They sometimes also contain kinds of peptides, substances whose molecules are combinations of two or simply just few proteins. The purpose of these substances is almost always to stimulate How To Remove Stretch Marks the fibroblasts in making more fibers which then is required to build up a firmer skin structure.